Publications

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Journal Article
M. Megraw, Mukherjee, S., and Ohler, U., “Sustained-input switches for transcription factors and microRNAs are central building blocks of eukaryotic gene circuits.”, Genome Biol, vol. 14, no. 8, p. R85, 2013.
S. M. Brady, Zhang, L., Megraw, M., Martinez, N. J., Jiang, E., Yi, C. S., Liu, W., Zeng, A., Taylor-Teeples, M., Kim, D., Ahnert, S., Ohler, U., Ware, D., Walhout, A. J. M., and Benfey, P. N., “A stele-enriched gene regulatory network in the Arabidopsis root.”, Mol Syst Biol, vol. 7, p. 459, 2011.
M. Megraw, Sethupathy, P., Corda, B., and Hatzigeorgiou, A. G., “miRGen: a database for the study of animal microRNA genomic organization and function.”, Nucleic Acids Res, vol. 35, no. Database issue, pp. D149-55, 2007.
P. Alexiou, Vergoulis, T., Gleditzsch, M., Prekas, G., Dalamagas, T., Megraw, M., Grosse, I., Sellis, T., and Hatzigeorgiou, A. G., “miRGen 2.0: a database of microRNA genomic information and regulation.”, Nucleic Acids Res, vol. 38, no. Database issue, pp. D137-41, 2010.
L. Zhang, Huang, J., Yang, N., Greshock, J., Megraw, M. S., Giannakakis, A., Liang, S., Naylor, T. L., Barchetti, A., Ward, M. R., Yao, G., Medina, A., O'brien-Jenkins, A., Katsaros, D., Hatzigeorgiou, A., Gimotty, P. A., Weber, B. L., and Coukos, G., “microRNAs exhibit high frequency genomic alterations in human cancer.”, Proc Natl Acad Sci U S A, vol. 103, no. 24, pp. 9136-41, 2006.
M. Megraw, Baev, V., Rusinov, V., Jensen, S. T., Kalantidis, K., and Hatzigeorgiou, A. G., “MicroRNA promoter element discovery in Arabidopsis.”, RNA, vol. 12, no. 9, pp. 1612-9, 2006.
M. Megraw and Hatzigeorgiou, A. G., “MicroRNA promoter analysis.”, Methods Mol Biol, vol. 592, pp. 149-61, 2010.
P. Sethupathy, Megraw, M., and Hatzigeorgiou, A. G., “A guide through present computational approaches for the identification of mammalian microRNA targets.”, Nat Methods, vol. 3, no. 11, pp. 881-6, 2006.
L. Zhang, Volinia, S., Bonome, T., Calin, G. Adrian, Greshock, J., Yang, N., Liu, C. - G., Giannakakis, A., Alexiou, P., Hasegawa, K., Johnstone, C. N., Megraw, M. S., Adams, S., Lassus, H., Huang, J., Kaur, S., Liang, S., Sethupathy, P., Leminen, A., Simossis, V. A., Sandaltzopoulos, R., Naomoto, Y., Katsaros, D., Gimotty, P. A., DeMichele, A., Huang, Q., Bützow, R., Rustgi, A. K., Weber, B. L., Birrer, M. J., Hatzigeorgiou, A. G., Croce, C. M., and Coukos, G., “Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer.”, Proc Natl Acad Sci U S A, vol. 105, no. 19, pp. 7004-9, 2008.
Y. Kawahara, Megraw, M., Kreider, E., Iizasa, H., Valente, L., Hatzigeorgiou, A. G., and Nishikura, K., “Frequency and fate of microRNA editing in human brain.”, Nucleic Acids Res, vol. 36, no. 16, pp. 5270-80, 2008.
H. Iizasa, Wulff, B. - E., Alla, N. R., Maragkakis, M., Megraw, M., Hatzigeorgiou, A., Iwakiri, D., Takada, K., Wiedmer, A., Showe, L., Lieberman, P., and Nishikura, K., “Editing of Epstein-Barr virus-encoded BART6 microRNAs controls their dicer targeting and consequently affects viral latency.”, J Biol Chem, vol. 285, no. 43, pp. 33358-70, 2010.