02128nas a2200421 4500008004100000022001400041245007500055210006900130260001300199300001200212490000700224520091800231653002801149653001501177653001201192653002101204653002601225653002301251653002801274653001101302653003801313653001301351653000901364653001401373653003601387653001301423653002601436100002401462700002401486700002301510700001901533700002401552700001801576700001601594700001801610700003001628856004801658 2010 eng d a1362-496200amiRGen 2.0: a database of microRNA genomic information and regulation.0 amiRGen 20 a database of microRNA genomic information and regulat c2010 Jan aD137-410 v383 a
MicroRNAs are small, non-protein coding RNA molecules known to regulate the expression of genes by binding to the 3'UTR region of mRNAs. MicroRNAs are produced from longer transcripts which can code for more than one mature miRNAs. miRGen 2.0 is a database that aims to provide comprehensive information about the position of human and mouse microRNA coding transcripts and their regulation by transcription factors, including a unique compilation of both predicted and experimentally supported data. Expression profiles of microRNAs in several tissues and cell lines, single nucleotide polymorphism locations, microRNA target prediction on protein coding genes and mapping of miRNA targets of co-regulated miRNAs on biological pathways are also integrated into the database and user interface. The miRGen database will be continuously maintained and freely available at http://www.microrna.gr/mirgen/.
10a3' Untranslated Regions10aAlgorithms10aAnimals10aCell Line, Tumor10aComputational Biology10aDatabases, Genetic10aDatabases, Nucleic Acid10aHumans10aInformation Storage and Retrieval10aInternet10aMice10aMicroRNAs10aPolymorphism, Single Nucleotide10aSoftware10aTranscription Factors1 aAlexiou, Panagiotis1 aVergoulis, Thanasis1 aGleditzsch, Martin1 aPrekas, George1 aDalamagas, Theodore1 aMegraw, Molly1 aGrosse, Ivo1 aSellis, Timos1 aHatzigeorgiou, Artemis, G uhttp://megraw.cgrb.oregonstate.edu/node/324